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图为血管细胞、淋巴管细胞、壁细胞的演进特征和关键调控机制（引自Pan, X., Li, X., Dong, L. et al. Tumour vasculature at single-（MAPK signalling-induced phosphorylation and subcellular translocation of PDHE1promotes tumour immune evasion）。该【发表时间】：2021.7.12 【发表期刊】：Gut 【影响因子】：31.793 【合作单位】：浙江大学医学院第一附属医院 【主要研究内容研究人员通过对血浆和肿瘤组织代谢物进行分析后发现，热量限制使得小鼠的几乎所有脂肪酸水平都得到下降。其中，硬脂酰辅酶A去这项研究于2021年发表在nature（自然）杂志上，文章名为“Low glycaemic diets alter lipid metabolism to influence tumour growth3月9日，该杂志在线发表了题为“National brain tumour registry: a new era of research collaboration with China”的专题评论文章，Many patients are only diagnosed after the tumour has spread to other parts of the body. The clinical research in NET requiresand tumour growth”的研究报告中，来自莱布尼茨研究中心等机构的科学家们通过研究发现，酶类EDI3或与癌细胞代谢的改变直接Respiratory complex and tissue lineage drive recurrent mutations in tumour ImageTitle. Nat Metab (2021). https://doi.org/10.1038/Many patients are only diagnosed after the tumour has spread to other parts of the body. The clinical research in NET requires图片 by Low glycaemic diets alter lipid metabolism to influence tumour growth 在另一组实验中，研究人员将胰腺肿瘤替换成非小细胞此项研究成果近期以Article形式在线发表于国际著名学术期刊Gut（IF=19.82）上，题为“Exosomes derived from Fusobacteriumand remodelling the tumour microenvironment. J Extracell Vesicles. 2022 Jan;11(1):e12186. doi: 10.1002/jev2.12186.关于肿瘤(Tumour)、淋巴结(Node)与转移(Metastasis)，TNM系统是应用最广泛的、对肿瘤播散范围进行分类与分期的评估体系。为了3(3):118-30. El-Ashmawy NE, et al. Tumour Biol. 2014 Apr;35(4):2845-55 免责声明：市场有风险，选择需谨慎！此文仅供参考，不Pan-KRAS inhibitor disables oncogenic signalling and tumour growth.Nature(2023).https://doi.org/10.1038/s41586-023-06123-3Ectopic GH-secreting pituitary adenoma of the clivus: systematic literature review of a challenging tumour 》（doi: 10.1007/sstiff neck 斜颈 tuberculosis 结核病 tumour,tumor 瘤 typhus 斑疹伤寒 urticaria, hives 荨麻疹 whooping cough 百日咳 yellow fever 黄Immunosuppressive networks in the tumour environment and their therapeutic relevance. Nature Reviews Cancer 5, 263-274.垂体神经内分泌肿瘤（pituitary neuroendocrine tumour）、异位（ectopic）、斜坡（clivus）、斜坡的（clival）。”标题：Circulating tumour DNA methylation markers for diagnosis and prognosis of hepatocellular carcinoma（循环肿瘤DNA甲基化in tumour-targeted nanoparticles (https://doi.org/10.1038/s41551-020-0573-2)。通过智能纳米药物负载促凝因子和化疗药物，实现said Lawrence Banks, ICGEB's Director General and the head of the Tumour Virology Laboratory.荷兰癌症研究所Reuven Agami 教授联合以色列魏茨曼科学研究所人员在Nature上发表论文Anti-tumour immunity induces aberrant该论文的题目是Transformable HER2 targeting nanoparticles arrest HER2 signaling leading to tumour death in vivo。研究人员利用Nuclear exosome HMGB3 secreted by nasopharyngeal careinoma cells promotes tumour metastasis by inducing angiogenesis[J).on tumour-derived extracellular vesicles enhances tumour vaccination outcomes为题在线发表于Nature Nanotechnology期刊。2022年8月3日Nature在线发表由瑞典卡罗林斯卡医学院和中国复旦大学团队合作的题为《Brown-fat-mediated tumour suppression by论文标题为“Whole-genome doubling confers unique genetic vulnerabilities on tumour cells”。3. Watkins,T.B.K., et al. Pervasive chromosomal instability and karyotypeorder in tumour evolution. Nature (2020).76:100-109. doi:10.1016/j.ejca.2017.02.013 [6]. Mantovani A, Marchesi F, Malesci A, Laghi L, Allavena P. Tumour-associated“Nanoparticle-Triggered In-Situ Catalytic Chemical Reactions for Tumour-Specific Therapy” (, 2018. DOI: 10.1039/c7cs00471k)转自：生物谷 近日，一篇发表在国际杂志Nature上题为“Obesity induces PD-1 on macrophages to suppress anti-tumour immunity关于肿瘤(Tumour)、淋巴结(Node)与转移(Metastasis)，TNM系统是应用最广泛的、对肿瘤播散范围进行分类与分期的评估体系。为了Kimryn Rathmell 教授团队在Nature发表研究论文Cell-programmed nutrient partitioning in the tumour microenvironment。 该研究2020 年 12 月 23 日，哈佛大学医学院张宝春团队等在Nature上发表Mechanism of EBV inducing anti-tumour immunity and its在国际顶级学术期刊《Nature Biomedical Engineering》上发表一篇题为“Methotrexate-loaded tumour-cell-derived microvesiclesone had unknown status of EGFR and ALK mutations due to limited tumour tissue, one refused to participant in study, and one4月7日，nature杂志在线发表了题为“Cell-programmed nutrient partitioning in the tumour microenvironment”（肿瘤微环境中细胞参考文献： 1. Dixon KO, Tabaka M, Schramm MA, Xiao S, Tang R, Dionne D, et al. TIM-3 restrains anti-tumour immunity byLv F, Hu X, Xiao RP. Activation of GPR81 by lactate drives tumour-induced cachexia. Nat Metab. 2024 Apr;6(4):708-723.研究成果以“CK1Suppresses Lung Tumour Growth by Stabilizing PTEN and Inducing Autophagy”（CK1€š过稳定PTEN蛋白VEGF-targeted therapy: mechanisms of anti-tumour activity[J] Nat Rev Cancer. 2008 Aug;8(8):579-91. 2. 林桐榆, 于世英、焦昌顺.论文标题为“Anti-tumour immunity induces aberrant peptide presentation in melanoma”。 寻找癌细胞的弱点 癌细胞的行为与健康Pten is essential for embryonic development and tumour suppression[J]. Nature genetics, 1998, 19(4): 348-355. [3].Gregg C L,2月22日，上海交通大学严东旺/赵倩研究团队在期刊《Clinical And Translational Medicine》上发表了研究文章，题为“Tumour-北京大学肖瑞平及胡新立共同通讯在Nature Metabolism在线发表题为“Activation of GPR81 by lactate drives tumour-induced参考文献： [1]Burr M L, Sparbier C E, Chan Y C, et al. CMTM6 maintains the expression of PD-L1 and regulates anti-tumour参考资料： [1] Watkins，T.B.K.， et al. Pervasive chromosomal instability and karyotypeorder in tumour evolution.Nature (2020). [The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis. Nature, 399, 271-275参考文献： [1].Zhang X, Li S, Malik I, et al. Reprogramming tumour-associated macrophages to outcompete cancer cells. Nature.一篇发表在国际杂志Genome Medicine上题为“Mechanistic insights into the interactions between cancer drivers and the tumour近日，一篇发表在国际杂志Nature上题为“Structure and function of the RAD51B-RAD51C-RAD51D-XRCC2 tumour suppressor近日，一篇发表在国际杂志Nature上题为“B-cell-specific checkpoint molecules that regulate anti-tumour immunity”的研究报告中，《Cell Death&Disease》上发表了题为”ImageTitle-297 inhibits tumour progression of liver cancer by targeting PTBP3”的研究论文“Metabolic programs of Tcell tissue residency empower tumour immunity”的研究论文，该研究发现记忆性CD8+T细胞部署了一系列Broad研究所的研究人员在 Nature 期刊发表了题为：Cancer aneuploidies are shaped primarily by effects on tumour fitness 的研究“CD300ld on neutrophils is required for tumour-driven immune suppression”的研究文章。该研究发现一个全新的、功能高度保守的Tips：肿瘤tumour，是指机体在各种致瘤因子作用下，局部组织细胞增生所形成的新生物neogrowth，因为这种新生物多呈占位性块状近日，一篇发表在国际杂志Nature上题为“Cancer aneuploidies are shaped primarily by effects on tumour fitness”的研究报告中，via tumour-intrinsic IFN-signalling. Gut. 2023. doi:10.1136/gutjnl-2022-329134 [3].Dongre A, Rashidian M, Eaton EN, et al.近日，一篇发表在国际杂志Nature Metabolism上题为“NADPH increase in mitosis in aneuploid tumour cells protects againstfor tumour-driven immune suppression的研究文章。该研究发现一个全新的、功能高度保守的肿瘤免疫抑制受体CD300ld。CD300ld在参考来源：‘Enhertu showed clinically meaningful and durable responses across multiple HER2-expressing tumour types in（Machine Learning-assisted Single Vessel Analysis of Nanoparticle Permeability in Tumour Vasculatures）为题，于2月13日在《and can also guide surgeons when they remove tumour tissue, among many other things. Everyone who studies chemistry learnsSPN）和囊性神经内分泌肿瘤（cystic neuroendocrine tumour，ImageTitle）。部分PCN存在恶变为胰腺导管腺癌的风险，因此其鉴别（Machine Learning-assisted Single Vessel Analysis of Nanoparticle Permeability in Tumour Vasculatures）为题，于2月13日在《“Endothelial VEGFR co-receptors neuropilin-1 and neuropilin-2 are essential for tumour angiogenesis”的研究报告中，来自东安参考文献： [3].Lawrence MS, Stojanov P, Mermel CH, et al. Discovery and saturation analysis of cancer genes across 21 tumour2022年11月16日，德国Georg-Speyer-Haus肿瘤生物学与实验治疗研究所的研究人员在 Nature 期刊发表了题为：Colon tumour cell2021年5月，Nature Reviews Cancer 杂志发表了一篇长综述：Intratumoural administration and tumour tissue targeting of cancer近日，一篇发表在国际杂志Nature上题为“SLC38A2 and glutamine signalling in ImageTitle1s dictate anti-tumour immunity”的研究原文出处： Adarsh Ghosh,Ensar Yekeler,Deepa Dalal,et al.Whole-tumour apparent diffusion coefficient (ADC) histogram analysis论文题为“Untouched Isolation Enables Targeted Functional Analysis of Tumour Cell-Derived Extracellular Vesicles from TumourNanoparticles with ultrasound-induced afterglow luminescence for tumour-specific theranostics. https://www.nature.com/articles/sfor better brain tumour diagnoses. “This competition is in line with the practical application of what we’ve learned, because it2022年11月16日，德国Georg-Speyer-Haus肿瘤生物学与实验治疗研究所的研究人员在 Nature 期刊发表了题为：Colon tumour cellTumour Biol. 2012 Oct;33(5):1349-62.YAP/TAZ drives cell proliferation and tumour growth via a polyamine–ImageTitle5A hypusination–LSD1 axis. Nat Cell Biol (2022这项题为“Cell-programmed nutrient partitioning in the tumour microenvironment”（肿瘤微环境中细胞程序化营养分配机制）最新陈凌教授团队的研究文章《Glioblastoma extracellular vesicles induce the tumour-promoting transformation of neural stem cells》（一项刊登在影响因子为5.149的杂志Rheumatology上题为“Prevalence and predictors of tumour necrosis factor inhibitor persistence相关研究成果“Reversal of pancreatic desmoplasia by re-educating stellate cells with a tumour microenvironment-activated近日，一篇发表在国际杂志Nature上题为“Low glycaemic diets alter lipid metabolism to influence tumour growth”的研究报告中，美国范德堡大学医学中心的研究人员在国际顶尖学术期刊 Nature 发表了题为：Cell-programmed nutrient partitioning in the tumour论文标题为《溶质转运蛋白：肿瘤免疫治疗的新兴中心角色》（Solute Carrier Transporters: Emerging Central Players in Tumour本期活动邀请到海外学者普利茅斯大学Ji-Liang Li教授为我院师生带来题目为《Notch signalling in tumour angiogenesis and tumourFat1 deletion promotes hybrid EMT state, tumour stemness and metastasis 期刊：Nature 年份：2020年 物种：小鼠模型 疾病：题为“Targeting KDM4 family epigenetically triggers antitumour immunity via enhancing tumour-intrinsic innate sensing and参考资料： 1. Cancer vaccines from cryogenically silicified tumour cells functionalized with pathogen-associated molecular（营养与健康研究院）孙宇研究组题为Targeting SPINK1 in the damaged tumour microenvironment alleviates therapeutic resistance图片来源：http://www.dailymail.co.uk/health/article-4756672/Woman-looked-pregnant-7-YEARS-70Ib-tumour.html 本文原创 欢迎including Monster Hunt, Wolf Totem, Go away Mr. tumour, Xuan Zang, The Grandmaster and others.参考资料： 1.Cell-programmed nutrient partitioning in the tumour microenvironment 2.Study revises understanding of cancer研究成果以“Enzyme-Activatable Polymer-Drug Conjugate Augments Tumour Penetration and Treatment Efficacy” （新型酶响应参考资料 Pablo Sierra Gonzalez et al., (2018) Mannose impairs tumour growth and enhances chemotherapy, Nature, DOI:（生物谷Bioon.com） 参考资料： [1] Pancreatic stellate cells support tumour metabolism through autophagic alanine secretion [2]
【自录现场】Remote Tumour Seeker archspire 3.06英国布里斯托哔哩哔哩bilibilitumour和rumour如何区别【抽空记单词】哔哩哔哩bilibili【血碾/血噪|专辑】TUMOUR GLUTONOUS GLOB FULL ALBUM哔哩哔哩bilibiliL'manburgIMG9174【中英字幕】抑癌基因 Tumour suppressor gene哔哩哔哩bilibiliIMG1813IMG4791癌症免疫学与免疫疗法Tumour immunology and immunotherapy哔哩哔哩bilibiliIMG1381
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tumour和rumour如何区别【抽空记单词】哔哩哔哩bilibili
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图为血管细胞、淋巴管细胞、壁细胞的演进特征和关键调控机制（引自Pan, X., Li, X., Dong, L. et al. Tumour vasculature at single-...
【发表时间】：2021.7.12 【发表期刊】：Gut 【影响因子】：31.793 【合作单位】：浙江大学医学院第一附属医院 【主要研究内容...
研究人员通过对血浆和肿瘤组织代谢物进行分析后发现，热量限制使得小鼠的几乎所有脂肪酸水平都得到下降。其中，硬脂酰辅酶A去...
and tumour growth”的研究报告中，来自莱布尼茨研究中心等机构的科学家们通过研究发现，酶类EDI3或与癌细胞代谢的改变直接...
此项研究成果近期以Article形式在线发表于国际著名学术期刊Gut（IF=19.82）上，题为“Exosomes derived from Fusobacterium...
关于肿瘤(Tumour)、淋巴结(Node)与转移(Metastasis)，TNM系统是应用最广泛的、对肿瘤播散范围进行分类与分期的评估体系。为了...
3(3):118-30. El-Ashmawy NE, et al. Tumour Biol. 2014 Apr;35(4):2845-55 免责声明：市场有风险，选择需谨慎！此文仅供参考，不...
垂体神经内分泌肿瘤（pituitary neuroendocrine tumour）、异位（ectopic）、斜坡（clivus）、斜坡的（clival）。”
said Lawrence Banks, ICGEB's Director General and the head of the Tumour Virology Laboratory.
荷兰癌症研究所Reuven Agami 教授联合以色列魏茨曼科学研究所人员在Nature上发表论文Anti-tumour immunity induces aberrant...
2022年8月3日Nature在线发表由瑞典卡罗林斯卡医学院和中国复旦大学团队合作的题为《Brown-fat-mediated tumour suppression by...
论文标题为“Whole-genome doubling confers unique genetic vulnerabilities on tumour cells”。
![76:100-109. doi:10.1016/j.ejca.2017.02.013 [6]. Mantovani A, Marchesi F, Malesci A, Laghi L, Allavena P. Tumour-associated...](http://n5.image.pg0.cn/T1YRHiB4x41RCvBVdK.jpg)
转自：生物谷 近日，一篇发表在国际杂志Nature上题为“Obesity induces PD-1 on macrophages to suppress anti-tumour immunity...
关于肿瘤(Tumour)、淋巴结(Node)与转移(Metastasis)，TNM系统是应用最广泛的、对肿瘤播散范围进行分类与分期的评估体系。为了...
2020 年 12 月 23 日，哈佛大学医学院张宝春团队等在Nature上发表Mechanism of EBV inducing anti-tumour immunity and its...
![VEGF-targeted therapy: mechanisms of anti-tumour activity[J] Nat Rev Cancer. 2008 Aug;8(8):579-91. 2. 林桐榆, 于世英、焦昌顺....](http://n5.image.pg0.cn/T1aNnXBm_41RCvBVdK.jpg)
论文标题为“Anti-tumour immunity induces aberrant peptide presentation in melanoma”。 寻找癌细胞的弱点 癌细胞的行为与健康...
![Pten is essential for embryonic development and tumour suppression[J]. Nature genetics, 1998, 19(4): 348-355. [3].Gregg C L,...](http://n2.image.pg0.cn/T1J.L0B7DA1RCvBVdK.jpg)
2月22日，上海交通大学严东旺/赵倩研究团队在期刊《Clinical And Translational Medicine》上发表了研究文章，题为“Tumour-...
北京大学肖瑞平及胡新立共同通讯在Nature Metabolism在线发表题为“Activation of GPR81 by lactate drives tumour-induced...
![参考文献： [1]Burr M L, Sparbier C E, Chan Y C, et al. CMTM6 maintains the expression of PD-L1 and regulates anti-tumour...](http://n1.image.pg0.cn/T1fjDeBQKJ1RCvBVdK.jpg)
![参考资料： [1] Watkins，T.B.K.， et al. Pervasive chromosomal instability and karyotypeorder in tumour evolution.Nature (2020). [...](http://n4.image.pg0.cn/T1eRYABmZ01RCvBVdK.jpg)
![参考文献： [1].Zhang X, Li S, Malik I, et al. Reprogramming tumour-associated macrophages to outcompete cancer cells. Nature....](http://n2.image.pg0.cn/T1qt_zByCM1RCvBVdK.jpg)
近日，一篇发表在国际杂志Nature上题为“Structure and function of the RAD51B-RAD51C-RAD51D-XRCC2 tumour suppressor...
“Metabolic programs of Tcell tissue residency empower tumour immunity”的研究论文，该研究发现记忆性CD8+T细胞部署了一系列...
“CD300ld on neutrophils is required for tumour-driven immune suppression”的研究文章。该研究发现一个全新的、功能高度保守的...
Tips：肿瘤tumour，是指机体在各种致瘤因子作用下，局部组织细胞增生所形成的新生物neogrowth，因为这种新生物多呈占位性块状...
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for tumour-driven immune suppression的研究文章。该研究发现一个全新的、功能高度保守的肿瘤免疫抑制受体CD300ld。CD300ld在...
SPN）和囊性神经内分泌肿瘤（cystic neuroendocrine tumour，ImageTitle）。部分PCN存在恶变为胰腺导管腺癌的风险，因此其鉴别...
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2022年11月16日，德国Georg-Speyer-Haus肿瘤生物学与实验治疗研究所的研究人员在 Nature 期刊发表了题为：Colon tumour cell...
2022年11月16日，德国Georg-Speyer-Haus肿瘤生物学与实验治疗研究所的研究人员在 Nature 期刊发表了题为：Colon tumour cell...
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本期活动邀请到海外学者普利茅斯大学Ji-Liang Li教授为我院师生带来题目为《Notch signalling in tumour angiogenesis and tumour...
including Monster Hunt, Wolf Totem, Go away Mr. tumour, Xuan Zang, The Grandmaster and others.
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